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human KPNA1 shRNA silencing Adenovirus

Name 
Ad-h-KPNA1-shRNA
Cat No 
shADV-213336
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KPNA1.

shADV-213336
Ad-h-KPNA1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KPNA1 (karyopherin subunit alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IPOA5; NPI-1; RCH2; SRP1
Description (Vector)
Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Two transcript variants, one protein-coding and the other not, have been found for this gene.
Gene ID
3836
Gene Name (Vector)
karyopherin subunit alpha 1
Gene Symbol
KPNA1
HGNC ID
HGNC:6394
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
RefSeq ID
NM_002264
RefSeq Synonyms
NM_002264, BC090864, BC003009, BC002374,
Species
human
UniGene ID
Hs.161008

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.