human KLK3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KLK3.
shADV-213291
Ad-h-KLK3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KLK3 (kallikrein-related peptidase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
APS; hK3; KLK2A1; PSA;
Description (Vector)
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Gene ID
354
Gene Name (Vector)
kallikrein-related peptidase 3
Gene Symbol
KLK3
HGNC ID
HGNC:6364
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_001648
RefSeq Synonyms
NM_001648, NM_001030050, NM_001030048, NM_001030047, BC056665, BC050595, BC005307,
Species
human
UniGene ID
Hs.171995
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.