human KLF8 shRNA silencing Adenovirus

Name
Ad-h-KLF8-shRNA

Cat No
shADV-213197

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human KLF8.

shADV-213197

Ad-h-KLF8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KLF8 (Kruppel like factor 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

BKLF3; ZNF741

Description (Vector)

KLF8 encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Gene ID

11279

Gene Name (Vector)

Kruppel like factor 8

Gene Symbol

KLF8

HGNC ID

HGNC:6351

ORF Size (aa)

1080

ORF Size (bp)

1080 bp

RefSeq ID

NM_007250

RefSeq Synonyms

NM_007250, NM_001324105, NM_001324104, NM_001324102, NM_001324100, NM_001324099, NM_001159296, BC112109, BC105130, BC031355,

Species

human

UniGene ID

Hs.646614

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.