human KLF4 shRNA silencing Adenovirus

Name 
Ad-h-KLF4-shRNA
Cat No 
shADV-213191
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KLF4.

shADV-213191
Ad-h-KLF4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KLF4 (Kruppel like factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; EZF; GKLF; gut Kruppel-like factor; gut-enriched krueppel-like factor; Krueppel-like factor 4; Kruppel-like factor 4 (gut)
Description (eCommerce)
KLF4 belongs to the Kruppel family of transcription factors. This zinc finger protein is required for normal development of the barrier function of skin. KLF4 is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. [taken from NCBI Entrez Gene (Gene ID: 9314)].
Gene ID
9314
Gene Name (eCommerce)
Kruppel like factor 4
Gene Name (Vector)
Kruppel like factor 4
Gene Symbol
KLF4
HGNC ID
HGNC:6348
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
Protein Name (eCommerce)
Krueppel-like factor 4
RefSeq ID
NM_004235
RefSeq Synonyms
NM_004235, NM_001314052, BC030811, BC029923,
Research Areas
Immunology,RNA Binding,Transcription Factor / Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,immunology,transcription_translation
Species
human
Target Sentence
KLF4 belongs to the Kruppel family of transcription factors. This zinc finger protein is required for normal development of the barrier function of skin. KLF4 is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. [taken from NCBI Entrez Gene (Gene ID: 9314)].
UniGene ID
Hs.376206
UniProt ID (eCommerce)
O43474

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.