human KLF11 shRNA silencing Adenovirus

Name 
Ad-h-KLF11-shRNA
Cat No 
shADV-213175
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KLF11.

shADV-213175
Ad-h-KLF11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KLF11 (Kruppel like factor 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FKLF; FKLF1; MODY7; TIEG2; Tieg3
Description (Vector)
KLF11 is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
8462
Gene Name (Vector)
Kruppel like factor 11
Gene Symbol
KLF11
HGNC ID
HGNC:11811
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_003597
RefSeq Synonyms
NM_003597, NM_001177718, NM_001177716, BC074922, BC069383, BC063286,
Species
human
UniGene ID
Hs.12229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.