human KLF10 shRNA silencing Adenovirus

Name
Ad-h-KLF10-shRNA

Cat No
shADV-213174

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human KLF10.

shADV-213174

Ad-h-KLF10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KLF10 (Kruppel like factor 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

early growth response-alpha; EGRA; EGR-alpha; Krueppel-like factor 10; TGFB-inducible early growth response protein 1; TIEG; TIEG1; TIEG-1; transforming growth factor-beta-inducible early growth response protein 1; zinc finger transcription factor TIEG

Description (eCommerce)

Transforming growth factor-beta inducible early gene 1 (TIEG1) is a member of the 3 zinc-finger family of Kruppel-like transcription factors. It is also known as Kruppel-like factor 10 (KLF10). TIEG1 functions as an inducer or repressor of gene transcription to regulate the actions of estrogen and TGFbeta signaling and influences the processes of proliferation, differentiation, and apoptosis.

Gene ID

7071

Gene Name (eCommerce)

Kruppel like factor 10

Gene Name (Vector)

Kruppel like factor 10

Gene Symbol

KLF10

HGNC ID

HGNC:11810

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1443

ORF Size (bp)

1443 bp

Protein Name (eCommerce)

Krueppel-like factor 10

RefSeq ID

NM_005655

RefSeq Synonyms

NM_005655, NM_001032282, BC095399, BC011538,

Research Areas

Apoptosis,Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Transforming growth factor-beta inducible early gene 1 (TIEG1) is a member of the 3 zinc-finger family of Kruppel-like transcription factors. It is also known as Kruppel-like factor 10 (KLF10). TIEG1 functions as an inducer or repressor of gene transcription to regulate the actions of estrogen and TGFbeta signaling and influences the processes of proliferation, differentiation, and apoptosis.

UniGene ID

Hs.435001

UniProt ID (eCommerce)

Q13118

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.