human KIF1C shRNA silencing Adenovirus

Name 
Ad-h-KIF1C-shRNA
Cat No 
shADV-213082
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KIF1C.

shADV-213082
Ad-h-KIF1C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KIF1C (kinesin family member 1C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
kinesin-like protein KIF1C; LTXS1; SATX2; SAX2; spastic ataxia 2 (autosomal recessive); SPAX2; SPG58
Description (eCommerce)
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF1C, also known as LTXS1 (lethal toxin sensitivity), has been found to be localized to the golgi and the endoplasmic reticulum (ER) and play a role in vesicle transport between the golgi and ER.
Gene ID
10749
Gene Name (eCommerce)
kinesin family member 1C
Gene Name (Vector)
kinesin family member 1C
Gene Symbol
KIF1C
HGNC ID
HGNC:6317
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3312
ORF Size (bp)
3312 bp
Protein Name (eCommerce)
Kinesin-like protein KIF1C
RefSeq ID
NM_006612
RefSeq Synonyms
NM_006612, BC034993,
Research Areas
Cytoskeleton,Golgi Apparatus,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
The kinesin superfamily of proteins consists of over forty KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. KIF1C, also known as LTXS1 (lethal toxin sensitivity), has been found to be localized to the golgi and the endoplasmic reticulum (ER) and play a role in vesicle transport between the golgi and ER.
UniGene ID
Hs.435120
UniProt ID (eCommerce)
O43896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.