Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human KIF11 shRNA silencing Adenovirus

Name 
Ad-h-KIF11-shRNA
Cat No 
shADV-213063
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KIF11.

shADV-213063
Ad-h-KIF11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KIF11 (kinesin family member 11). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EG5; HKSP; kinesin-like protein 1; kinesin-like protein KIF11; kinesin-like spindle protein HKSP; kinesin-related motor protein Eg5; KNSL1; MCLMR; thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP5; TRIP-5
Description (eCommerce)
The kinesin superfamily of proteins consists of forty five KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. EG5/KIF11 plays a role in spindle-pole formation and chromosome positioning and separation.
Description (Vector)
KIF11 encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
Gene ID
3832
Gene Name (eCommerce)
kinesin family member 11
Gene Name (Vector)
kinesin family member 11
Gene Symbol
KIF11
HGNC ID
HGNC:6388
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3171
ORF Size (bp)
3171 bp
Protein Name (eCommerce)
Kinesin-like protein KIF11
RefSeq ID
NM_004523
RefSeq Synonyms
NM_004523, BC136474, BC126211,
Research Areas
Antigen Processing and Presentation,Cell Cycle,Cell Division,Chromatin Remodeling,Cytoskeleton,Immunology
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,immunology
Species
human
Target Sentence
The kinesin superfamily of proteins consists of forty five KIF motor proteins that function in intracellular transport along microtubules. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. EG5/KIF11 plays a role in spindle-pole formation and chromosome positioning and separation.
UniGene ID
Hs.8878
UniProt ID (eCommerce)
P52732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.