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human KIAA1429 shRNA silencing Adenovirus

Name 
Ad-h-KIAA1429-shRNA
Cat No 
shADV-213006
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KIAA1429.

shADV-213006
Ad-h-KIAA1429-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KIAA1429 (KIAA1429). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
88
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
fSAP121; functional spliceosome-associated protein 121; KIAA1429; MSTP054; protein virilizer homolog; virilizer homolog
Description (eCommerce)
The virilizer (vir) gene was discovered as a factor required for dosage compensation and sex determination in female flies. In drosophila it has been determined to function as a positive regulator of female-specific mRNA splicing. Database searches using the deduced amino acid sequence of the drosophila VIR retrieved a human protein BAA92667 (GenBank) which corresponds to the gene designated as KIAA1429. The human protein is 28% identical and about 40% similar to drosophila VIR and contains the putative transmembrane domain of drosophila VIR.
Gene ID
25962
Gene Name (eCommerce)
vir like m6A methyltransferase associated
Gene Name (Vector)
KIAA1429
Gene Symbol
KIAA1429
HGNC ID
HGNC:24500
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3444
ORF Size (bp)
3444 bp
Protein Name (eCommerce)
Protein virilizer homolog
RefSeq ID
NM_015496
RefSeq Synonyms
NM_183009, NM_015496, BC113380, BC112288,
Research Areas
Cell Biology,mRNA Processing,mRNA Splicing,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
The virilizer (vir) gene was discovered as a factor required for dosage compensation and sex determination in female flies. In drosophila it has been determined to function as a positive regulator of female-specific mRNA splicing. Database searches using the deduced amino acid sequence of the drosophila VIR retrieved a human protein BAA92667 (GenBank) which corresponds to the gene designated as KIAA1429. The human protein is 28% identical and about 40% similar to drosophila VIR and contains the putative transmembrane domain of drosophila VIR.
UniGene ID
Hs.202238
UniProt ID (eCommerce)
Q69YN4

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.