human KCNV2 shRNA silencing Adenovirus

Name
Ad-h-KCNV2-shRNA

Cat No
shADV-212794

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human KCNV2.

shADV-212794

Ad-h-KCNV2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNV2 (potassium voltage-gated channel modifier subfamily V member 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

KV11.1; Kv8.2; RCD3B

Description (Vector)

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

Gene ID

169522

Gene Name (Vector)

potassium voltage-gated channel modifier subfamily V member 2

Gene Symbol

KCNV2

HGNC ID

HGNC:19698

ORF Size (aa)

1638

ORF Size (bp)

1638 bp

RefSeq ID

NM_133497

RefSeq Synonyms

NM_133497, BC101353, BC101352,

Species

human

UniGene ID

Hs.660831

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.