human KCNE3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human KCNE3.
shADV-212687
Ad-h-KCNE3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNE3 (potassium voltage-gated channel subfamily E regulatory subunit 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HOKPP; HYPP; MiRP2
Description (Vector)
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis.
Gene ID
10008
Gene Name (Vector)
potassium voltage-gated channel subfamily E regulatory subunit 3
Gene Symbol
KCNE3
HGNC ID
HGNC:6243
ORF Size (aa)
312
RefSeq ID
NM_005472
RefSeq Synonyms
NM_005472, BC113743, BC110612, BC032235,
Species
human
UniGene ID
Hs.523899
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.