human KCNE1 shRNA silencing Adenovirus

Name 
Ad-h-KCNE1-shRNA
Cat No 
shADV-212683
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human KCNE1.

shADV-212683
Ad-h-KCNE1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KCNE1 (potassium voltage-gated channel subfamily E regulatory subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ISK; JLNS; JLNS2; LQT2/5; LQT5; MinK
Description (Vector)
The product of this gene belongs to the potassium channel KCNE family. Potassium ion channels are essential to many cellular functions and show a high degree of diversity, varying in their electrophysiologic and pharmacologic properties. This gene encodes a transmembrane protein known to associate with the product of the KVLQT1 gene to form the delayed rectifier potassium channel. Mutation in this gene are associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
3753
Gene Name (Vector)
potassium voltage-gated channel subfamily E regulatory subunit 1
Gene Symbol
KCNE1
HGNC ID
HGNC:6240
ORF Size (aa)
390
RefSeq ID
NM_000219
RefSeq Synonyms
NM_001270405, NM_001270404, NM_001270403, NM_001270402, NM_001127670, NM_001127669, NM_001127668, NM_000219, BC046224, BC036452,
Species
human
UniGene ID
Hs.121495

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.