human JAK3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human JAK3.
shADV-212574
Ad-h-JAK3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human JAK3 (Janus kinase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
Description (Vector)
JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Gene ID
3718
Gene Name (Vector)
Janus kinase 3
Gene Symbol
JAK3
HGNC ID
HGNC:6193
ORF Size (aa)
1860
ORF Size (bp)
1860 bp
RefSeq ID
NM_000215
RefSeq Synonyms
NM_000215, BC028068,
Species
human
UniGene ID
Hs.515247
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.