human ITPKB shRNA silencing Adenovirus

Name 
Ad-h-ITPKB-shRNA
Cat No 
shADV-212547
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ITPKB.

shADV-212547
Ad-h-ITPKB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ITPKB (inositol-trisphosphate 3-kinase B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IP3-3KB; IP3K; IP3K-B; IP3KB; PIG37
Description (Vector)
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Gene ID
3707
Gene Name (Vector)
inositol-trisphosphate 3-kinase B
Gene Symbol
ITPKB
HGNC ID
HGNC:6179
ORF Size (aa)
1935
ORF Size (bp)
1935 bp
RefSeq ID
NM_002221
RefSeq Synonyms
NM_002221, BC015009,
Species
human
UniGene ID
Hs.659396

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.