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human ITGA3 shRNA silencing Adenovirus

Name 
Ad-h-ITGA3-shRNA
Cat No 
shADV-212477
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ITGA3.

shADV-212477
Ad-h-ITGA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ITGA3 (integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD49C; FLJ34631; FLJ34704; GAP-B3; GAPB3; MSK18; VCA-2; VL3A; VLA3a;
Description (Vector)
ITGA3 belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
3675
Gene Name (Vector)
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Gene Symbol
ITGA3
HGNC ID
HGNC:6139
ORF Size (aa)
3156
ORF Size (bp)
3156 bp
RefSeq ID
NM_002204
RefSeq Synonyms
NM_005501, NM_002204, BC150190, BC144328, BC136636,
Species
human
UniGene ID
Hs.265829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.