human ISCA2 shRNA silencing Adenovirus

Name 
Ad-h-ISCA2-shRNA
Cat No 
shADV-212431
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ISCA2.

shADV-212431
Ad-h-ISCA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ISCA2 (iron-sulfur cluster assembly 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
c14_5557; HBLD1; HESB-like domain-containing protein 1; iron-sulfur cluster assembly 2 homolog, mitochondrial; ISA2; MMDS4
Description (eCommerce)
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86U28].
Gene ID
122961
Gene Name (eCommerce)
iron-sulfur cluster assembly 2
Gene Name (Vector)
iron-sulfur cluster assembly 2
Gene Symbol
ISCA2
HGNC ID
HGNC:19857
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
465
ORF Size (bp)
465 bp
Protein Name (eCommerce)
Iron-sulfur cluster assembly 2 homolog, mitochondrial
RefSeq ID
NM_194279
RefSeq Synonyms
NM_194279, NM_001272007, BC032893, BC015771,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86U28].
UniGene ID
Hs.709509
UniProt ID (eCommerce)
Q86U28

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.