human IRF2BP1 shRNA silencing Adenovirus

Name
Ad-h-IRF2BP1-shRNA

Cat No
shADV-212401

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human IRF2BP1.

shADV-212401

Ad-h-IRF2BP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IRF2BP1 (interferon regulatory factor 2 binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

No

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; IRF-2BP1; probable E3 ubiquitin-protein ligase IRF2BP1; probable RING-type E3 ubiquitin transferase IRF2BP1

Description (eCommerce)

Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.

Gene ID

26145

Gene Name (eCommerce)

interferon regulatory factor 2 binding protein 1

Gene Name (Vector)

interferon regulatory factor 2 binding protein 1

Gene Symbol

IRF2BP1

HGNC ID

HGNC:21728

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1755

ORF Size (bp)

1755 bp

Protein Name (eCommerce)

Interferon regulatory factor 2-binding protein 1

RefSeq ID

NM_015649

RefSeq Synonyms

NM_015649, BC078181, BC039002, BC038222,

Research Areas

Signal Transduction,TGF-beta Signaling,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Interferon regulatory factor-2-binding protein-2 (IRF2BP1) is a transcriptional co-repressor of IRF2 (interferon regulatory factor-2). IRF2BP2 has also been shown to play a role in cell survival during stress responses involving p53. IRF2BP2 is also a component of the TEAD4/BGLL4 transcription factor complex involved in the regulation of VEGFA expression.

UniGene ID

Hs.515477

UniProt ID (eCommerce)

Q8IU81

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.