human INTS8 shRNA silencing Adenovirus

Name 
Ad-h-INTS8-shRNA
Cat No 
shADV-212329
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human INTS8.

shADV-212329
Ad-h-INTS8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human INTS8 (integrator complex subunit 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C8orf52; INT8; integrator complex subunit 8; protein kaonashi-1
Description (eCommerce)
The epitope recognized by IHC-00415 maps to a region between residues 200 and 250 of human INT8 using the numbering given in SwissProt entry Q75QN2 (GeneID 55656).
Description (Vector)
INTS8 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
Gene ID
55656
Gene Name (eCommerce)
integrator complex subunit 8
Gene Name (Vector)
integrator complex subunit 8
Gene Symbol
INTS8
HGNC ID
HGNC:26048
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2988
ORF Size (bp)
2988 bp
Protein Name (eCommerce)
Integrator complex subunit 8
RefSeq ID
NM_017864
RefSeq Synonyms
NM_017864, BC136754,
Research Areas
RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
The epitope recognized by IHC-00415 maps to a region between residues 200 and 250 of human INT8 using the numbering given in SwissProt entry Q75QN2 (GeneID 55656).
UniGene ID
Hs.521693
UniProt ID (eCommerce)
Q75QN2

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.