human INTS12 shRNA silencing Adenovirus

Name 
Ad-h-INTS12-shRNA
Cat No 
shADV-212317
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human INTS12.

shADV-212317
Ad-h-INTS12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human INTS12 (integrator complex subunit 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
INT12; PHF22; SBBI22
Description (Vector)
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
Gene ID
57117
Gene Name (Vector)
integrator complex subunit 12
Gene Symbol
INTS12
HGNC ID
HGNC:25067
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_020395
RefSeq Synonyms
NM_020395, NM_001142471, BC014442,
Species
human
UniGene ID
Hs.480454

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.