human INHBA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human INHBA.
shADV-212270
Ad-h-INHBA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human INHBA (inhibin beta A subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EDF; FRP
Description (Vector)
The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Gene ID
3624
Gene Name (Vector)
inhibin beta A subunit
Gene Symbol
INHBA
HGNC ID
HGNC:6066
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_002192
RefSeq Synonyms
NM_002192, BC007858,
Species
human
UniGene ID
Hs.583348
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.