human IL21 shRNA silencing Adenovirus

Name
Ad-h-IL21-shRNA

Cat No
shADV-212139

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human IL21.

shADV-212139

Ad-h-IL21-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IL21 (interleukin 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CVID11; IL-21; Za11

Description (Vector)

IL21 encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

59067

Gene Name (Vector)

interleukin 21

Gene Symbol

IL21

HGNC ID

HGNC:6005

ORF Size (aa)

489

RefSeq ID

NM_021803

RefSeq Synonyms

NM_021803, NM_001207006, BC069124, BC066262, BC066261, BC066260, BC066259, BC066258,

Species

human

UniGene ID

Hs.567559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.