human IL12A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human IL12A.
shADV-212027
Ad-h-IL12A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human IL12A (interleukin 12A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLMF; IL-12A; NFSK; NKSF1; P35
Description (Vector)
IL12A encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Gene ID
3592
Gene Name (Vector)
interleukin 12A
Gene Symbol
IL12A
HGNC ID
HGNC:5969
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_000882
RefSeq Synonyms
NM_000882, BC104984, BC104982,
Species
human
UniGene ID
Hs.673
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.