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human IL11RA shRNA silencing Adenovirus

Name 
Ad-h-IL11RA-shRNA
Cat No 
shADV-212026
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human IL11RA.

shADV-212026
Ad-h-IL11RA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IL11RA (interleukin 11 receptor, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MGC2146;
Description (Vector)
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
3590
Gene Name (Vector)
interleukin 11 receptor, alpha
Gene Symbol
IL11RA
HGNC ID
HGNC:5967
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_004512
RefSeq Synonyms
NM_147162, NM_004512, NM_001142784, BC003110,
Species
human
UniGene ID
Hs.591088

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.