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human IFNGR2 shRNA silencing Adenovirus

Name 
Ad-h-IFNGR2-shRNA
Cat No 
shADV-211878
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human IFNGR2.

shADV-211878
Ad-h-IFNGR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human IFNGR2 (interferon gamma receptor 2 (interferon gamma transducer 1)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AF-1; IFGR2; IFNGT1; IMD28
Description (Vector)
IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
Gene ID
3460
Gene Name (Vector)
interferon gamma receptor 2 (interferon gamma transducer 1)
Gene Symbol
IFNGR2
HGNC ID
HGNC:5440
ORF Size (aa)
1014
ORF Size (bp)
1014 bp
RefSeq ID
NM_005534
RefSeq Synonyms
NM_005534, NM_001329128, BC003624,
Species
human
UniGene ID
Hs.634632

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.