human HOXB8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HOXB8.
shADV-211460
Ad-h-HOXB8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HOXB8 (homeobox B8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Hox-2.4; HOX2; HOX2D
Description (Vector)
HOXB8 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
Gene ID
3218
Gene Name (Vector)
homeobox B8
Gene Symbol
HOXB8
HGNC ID
HGNC:5119
ORF Size (aa)
729
ORF Size (bp)
729 bp
RefSeq ID
NM_024016
RefSeq Synonyms
NM_024016, BC141560,
Species
human
UniGene ID
Hs.514292
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.