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human HNRNPUL1 shRNA silencing Adenovirus

Name 
Ad-h-HNRNPUL1-shRNA
Cat No 
shADV-211392
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HNRNPUL1.

shADV-211392
Ad-h-HNRNPUL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HNRNPUL1 (heterogeneous nuclear ribonucleoprotein U like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
adenovirus early region 1B-associated protein 5; E1B 55kDa associated protein 5; E1B-55 kDa-associated protein 5; E1BAP5; E1B-AP5; heterogeneous nuclear ribonucleoprotein U-like protein 1; HNRPUL1
Description (eCommerce)
E1B-AP5 was identified as a protein that interacts with adenovirus type 5 (Ad5) early 55-kDa oncoprotein. EIB-AP5 is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family that can bind RNA and appears to play a role in mRNA processing and transport.
Description (Vector)
HNRNPUL1 encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined.
Gene ID
11100
Gene Name (eCommerce)
heterogeneous nuclear ribonucleoprotein U like 1
Gene Name (Vector)
heterogeneous nuclear ribonucleoprotein U like 1
Gene Symbol
HNRNPUL1
HGNC ID
HGNC:17011
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2415
ORF Size (bp)
2415 bp
Protein Name (eCommerce)
Heterogeneous nuclear ribonucleoprotein U-like protein 1
RefSeq ID
NM_007040
RefSeq Synonyms
NM_144732, NM_007040, NM_001321211, NM_001321208, NM_001301016, BC027713, BC014232, BC009988, BC002564,
Research Areas
Gene Expression,Host-Virus Interactions,mRNA Processing,mRNA Splicing,Response to Virus,RNA Binding,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
E1B-AP5 was identified as a protein that interacts with adenovirus type 5 (Ad5) early 55-kDa oncoprotein. EIB-AP5 is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family that can bind RNA and appears to play a role in mRNA processing and transport.
UniGene ID
Hs.718642
UniProt ID (eCommerce)
Q9BUJ2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.