human HNRNPD shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HNRNPD.
shADV-211371
Ad-h-HNRNPD-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HNRNPD (heterogeneous nuclear ribonucleoprotein D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AUF1; AUF1A; hnRNPD0; HNRPD; P37
Description (Vector)
HNRNPD belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
Gene ID
3184
Gene Name (Vector)
heterogeneous nuclear ribonucleoprotein D
Gene Symbol
HNRNPD
HGNC ID
HGNC:5036
ORF Size (aa)
1068
ORF Size (bp)
1068 bp
RefSeq ID
NM_031370
RefSeq Synonyms
NM_031370, NM_031369, NM_002138, NM_001003810, BC026015, BC023977, BC002401,
Species
human
UniGene ID
Hs.480073
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.