human HNF1A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HNF1A.
shADV-211324
Ad-h-HNF1A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HNF1A (HNF1 homeobox A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
albumin proximal factor; hepatic nuclear factor 1; hepatocyte nuclear factor 1-alpha; HNF1; HNF-1A; HNF-1-alpha; HNF4A; IDDM20; interferon production regulator factor; LFB1; liver-specific transcription factor LF-B1; MODY3; TCF1; TCF-1; Transcription factor 1; transcription factor 1, hepatic; truncated hepatocyte nuclear factor 1 alpha
Description (eCommerce)
Hepatocyte nuclear factor 1-alpha (HNF1-Alpha) is a transcription factor required for the expression of several liver-specific genes. HNF1-Alpha functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in the HNF1A gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas [taken from NCBI Entrez Gene (Gene ID: 6927)].
Description (Vector)
HNF1A is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
Gene ID
6927
Gene Name (eCommerce)
HNF1 homeobox A
Gene Name (Vector)
HNF1 homeobox A
Gene Symbol
HNF1A
HGNC ID
HGNC:11621
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
Protein Name (eCommerce)
Hepatocyte nuclear factor 1-alpha
RefSeq ID
NM_000545
RefSeq Synonyms
NM_001306179, NM_000545, BC104910, BC104908,
Research Areas
Chromatin Remodeling,Metabolism/Metabolic Process,Notch Signaling,Signal Transduction,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,transcription_translation,metabolism,signal_transduction,developmental_biology,genetics,transcription_translation,signal_transduction,developmental_biology
Species
human
Target Sentence
Hepatocyte nuclear factor 1-alpha (HNF1-Alpha) is a transcription factor required for the expression of several liver-specific genes. HNF1-Alpha functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in the HNF1A gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas [taken from NCBI Entrez Gene (Gene ID: 6927)].
UniGene ID
Hs.654455
UniProt ID (eCommerce)
P20823
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.