human CSF1R shRNA silencing Adenovirus

Name
Ad-h-CSF1R-shRNA

Cat No
shADV-211307

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CSF1R.

shADV-211307

Ad-h-CSF1R-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CSF1R (colony stimulating factor 1 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R

Description (Vector)

CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Gene ID

1436

Gene Name (Vector)

colony stimulating factor 1 receptor

Gene Symbol

CSF1R

HGNC ID

HGNC:2433

ORF Size (aa)

2919

ORF Size (bp)

2919 bp

RefSeq ID

NM_005211

RefSeq Synonyms

NM_005211, NM_001288705, BC047521,

Species

human

UniGene ID

Hs.586219

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.