Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human HMG20B shRNA silencing Adenovirus

Name 
Ad-h-HMG20B-shRNA
Cat No 
shADV-211257
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HMG20B.

shADV-211257
Ad-h-HMG20B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HMG20B (high mobility group 20B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BRAF25; BRAF35; BRCA2-associated factor 35; HMG box domain containing 2; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; HMGX2; HMGXB2; PP7706; pp8857; SMARCE1r; SMARCE1-related protein; SOXL; Sox-like transcriptional factor; structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1-related
Description (eCommerce)
HMG20B/BRAF35 was originally identified as a factor that interacted with the BRCA2 multiprotein-complex. In association with BRCA2, HMG20B/BRAF35 plays a role in mitotic progression. HMG20B also associates with a six-subunit BRCA2-devoid complex similar to SWI/SNF and NuRD that displays deacetylating and chromatin-remodeling activity and mediates repression of neuron-specific genes.
Gene ID
10362
Gene Name (eCommerce)
high mobility group 20B
Gene Name (Vector)
high mobility group 20B
Gene Symbol
HMG20B
HGNC ID
HGNC:5002
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
648
ORF Size (bp)
648 bp
Protein Name (eCommerce)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
RefSeq ID
NM_006339
RefSeq Synonyms
NM_006339, BC021585, BC004408, BC003505, BC002552,
Research Areas
Cell Cycle,Chromatin Remodeling,Neurobiology,Transcription Factor/Regulator,Translational Control
Research Areas (Faceted)
cell_biology,cell_cycle,transcription_translation,neurobiology,genetics
Species
human
Target Sentence
HMG20B/BRAF35 was originally identified as a factor that interacted with the BRCA2 multiprotein-complex. In association with BRCA2, HMG20B/BRAF35 plays a role in mitotic progression. HMG20B also associates with a six-subunit BRCA2-devoid complex similar to SWI/SNF and NuRD that displays deacetylating and chromatin-remodeling activity and mediates repression of neuron-specific genes.
UniGene ID
Hs.406534
UniProt ID (eCommerce)
Q9P0W2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.