human HLX shRNA silencing Adenovirus

Name 
Ad-h-HLX-shRNA
Cat No 
shADV-211245
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HLX.

shADV-211245
Ad-h-HLX-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HLX (H2.0 like homeobox). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
53
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H2.0-like homeo box-1; H2.0-like homeobox 1; H2.0-like homeobox protein; HB24; HLX1; homeobox protein HB24; homeobox protein HLX1
Description (eCommerce)
H2.0-like homeobox protein (HLX) is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. HLX is involved in embryogenesis and hematopoiesis (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14774].
Gene ID
3142
Gene Name (eCommerce)
H2.0 like homeobox
Gene Name (Vector)
H2.0 like homeobox
Gene Symbol
HLX
HGNC ID
HGNC:4978
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1467
ORF Size (bp)
1467 bp
Protein Name (eCommerce)
H2.0-like homeobox protein
RefSeq ID
NM_021958
RefSeq Synonyms
NM_021958, BC033808, BC007294,
Research Areas
Interleukin Signaling,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
H2.0-like homeobox protein (HLX) is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. HLX is involved in embryogenesis and hematopoiesis (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q14774].
UniGene ID
Hs.74870
UniProt ID (eCommerce)
Q14774

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.