human HK2 shRNA silencing Adenovirus

Name 
Ad-h-HK2-shRNA
Cat No 
shADV-211204
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human HK2.

shADV-211204
Ad-h-HK2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HK2 (hexokinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HKII; HXK2
Description (Vector)
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Gene ID
3099
Gene Name (Vector)
hexokinase 2
Gene Symbol
HK2
HGNC ID
HGNC:4923
ORF Size (aa)
2754
ORF Size (bp)
2754 bp
RefSeq ID
NM_000189
RefSeq Synonyms
NM_000189, BC064369, BC021116,
Species
human
UniGene ID
Hs.591588

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.