human HIST1H4B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HIST1H4B.
shADV-211148
Ad-h-HIST1H4B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HIST1H4B (histone cluster 1 H4 family member b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H4/I; H4FI
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Gene ID
8366
Gene Name (Vector)
histone cluster 1 H4 family member b
Gene Symbol
HIST1H4B
HGNC ID
HGNC:4789
ORF Size (aa)
312
RefSeq ID
NM_003544
RefSeq Synonyms
NM_003544, BC069467,
Species
human
UniGene ID
Hs.143080
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.