human HIST1H2BB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HIST1H2BB.
shADV-211094
Ad-h-HIST1H2BB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HIST1H2BB (histone cluster 1 H2B family member b). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
H2B.1; H2B/f; H2BFF
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Gene ID
3018
Gene Name (Vector)
histone cluster 1 H2B family member b
Gene Symbol
HIST1H2BB
HGNC ID
HGNC:4751
ORF Size (aa)
381
RefSeq ID
NM_021062
RefSeq Synonyms
NM_021062, BC096728,
Species
human
UniGene ID
Hs.553494
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.