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human HIST1H2AE shRNA silencing Adenovirus

Name 
Ad-h-HIST1H2AE-shRNA
Cat No 
shADV-211071
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human HIST1H2AE.

shADV-211071
Ad-h-HIST1H2AE-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HIST1H2AE (histone cluster 1 H2A family member e). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
H2A.1; H2A.2; H2A/a; H2AFA
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Gene ID
3012
Gene Name (Vector)
histone cluster 1 H2A family member e
Gene Symbol
HIST1H2AE
HGNC ID
HGNC:4724
ORF Size (aa)
393
RefSeq ID
NM_021052
RefSeq Synonyms
NM_021052, BC093862, BC093836,
Species
human
UniGene ID
Hs.121017

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.