human HIRIP3 shRNA silencing Adenovirus

Name 
Ad-h-HIRIP3-shRNA
Cat No 
shADV-211047
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human HIRIP3.

shADV-211047
Ad-h-HIRIP3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human HIRIP3 (HIRA interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
8479
Gene Name (Vector)
HIRA interacting protein 3
Gene Symbol
HIRIP3
HGNC ID
HGNC:4917
ORF Size (aa)
1671
ORF Size (bp)
1671 bp
RefSeq ID
NM_003609
RefSeq Synonyms
NM_003609, NM_001197323, BC000588,
Species
human
UniGene ID
Hs.592046

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.