human HEY2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HEY2.
shADV-210988
Ad-h-HEY2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HEY2 (hes related family bHLH transcription factor with YRPW motif 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHb32; CHF1; GRIDLOCK; GRL; HERP1; HESR2; HRT2
Description (Vector)
HEY2 encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Gene ID
23493
Gene Name (Vector)
hes related family bHLH transcription factor with YRPW motif 2
Gene Symbol
HEY2
HGNC ID
HGNC:4881
ORF Size (aa)
1014
ORF Size (bp)
1014 bp
RefSeq ID
NM_012259
RefSeq Synonyms
NM_012259, BC007707,
Species
human
UniGene ID
Hs.144287
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.