human HERV-FRD shRNA silencing Adenovirus

Name 
Ad-h-HERV-FRD-shRNA
Cat No 
shADV-210962
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ERVFRD-1.

shADV-210962
Ad-h-HERV-FRD-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ERVFRD-1 (endogenous retrovirus group FRD member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
envFRD; ERVFRDE1; GLLL6191; HERV-FRD; HERV-W/FRD; UNQ6191
Description (Vector)
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Gene ID
405754
Gene Name (Vector)
endogenous retrovirus group FRD member 1
Gene Symbol
ERVFRD-1
HGNC ID
HGNC:33823
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
RefSeq ID
NM_207582
RefSeq Synonyms
NM_207582, BC068585,
Species
human
UniGene ID
Hs.631996

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.