human HAP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human HAP1.
shADV-210778
Ad-h-HAP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human HAP1 (huntingtin associated protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HAP2; hHLP1; HIP5; HLP
Description (Vector)
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
9001
Gene Name (Vector)
huntingtin associated protein 1
Gene Symbol
HAP1
HGNC ID
HGNC:4812
ORF Size (aa)
2016
ORF Size (bp)
2016 bp
RefSeq ID
NM_001079870
RefSeq Synonyms
NM_177977, NM_001079871, NM_001079870, BC156728,
Species
human
UniGene ID
Hs.158300
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.