human GTF3C1 shRNA silencing Adenovirus

Name 
Ad-h-GTF3C1-shRNA
Cat No 
shADV-210652
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GTF3C1.

shADV-210652
Ad-h-GTF3C1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GTF3C1 (general transcription factor IIIC subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
general transcription factor 3C polypeptide 1; general transcription factor IIIC, polypeptide 1 (alpha subunit); general transcription factor IIIC, polypeptide 1, alpha 220kDa; TF3C-alpha; TFIIIC; TFIIIC 220 kDa subunit; TFIIIC box B-binding subunit; TFIIIC220; TFIIICalpha; transcription factor IIIC 220 kDa subunit; transcription factor IIIC subunit alpha
Description (eCommerce)
General transcription factor 3C polypeptide 1 (GTF3C1/TFIIIC220) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C1/TFIIIC220 to the TFIIIC complex has not been fully determined.
Gene ID
2975
Gene Name (eCommerce)
general transcription factor IIIC subunit 1
Gene Name (Vector)
general transcription factor IIIC subunit 1
Gene Symbol
GTF3C1
HGNC ID
HGNC:4664
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
6330
ORF Size (bp)
6330 bp
Protein Name (eCommerce)
General transcription factor 3C polypeptide 1
RefSeq ID
NM_001520
RefSeq Synonyms
NM_001520, NM_001286242, BC137229,
Research Areas
Gene Expression,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
General transcription factor 3C polypeptide 1 (GTF3C1/TFIIIC220) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C1/TFIIIC220 to the TFIIIC complex has not been fully determined.
UniGene ID
Hs.371718
UniProt ID (eCommerce)
Q12789

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.