human GTF2E2 shRNA silencing Adenovirus

Name 
Ad-h-GTF2E2-shRNA
Cat No 
shADV-210635
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GTF2E2.

shADV-210635
Ad-h-GTF2E2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GTF2E2 (general transcription factor IIE subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FE; General transcription factor IIE subunit 2; general transcription factor IIE, polypeptide 2, beta 34kDa; TF2E2; TFIIE beta subunit; TFIIE-B; TFIIE-beta; transcription initiation factor IIE subunit beta; TTD6
Description (eCommerce)
GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29084].
Gene ID
2961
Gene Name (eCommerce)
general transcription factor IIE subunit 2
Gene Name (Vector)
general transcription factor IIE subunit 2
Gene Symbol
GTF2E2
HGNC ID
HGNC:4651
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
876
ORF Size (bp)
876 bp
Protein Name (eCommerce)
Transcription initiation factor IIE subunit beta
RefSeq ID
NM_002095
RefSeq Synonyms
NM_002095, BC030572,
Research Areas
Cancer,Gene Expression,Host-Virus Interactions,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P29084].
UniGene ID
Hs.77100
UniProt ID (eCommerce)
P29084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.