human GPSN2 shRNA silencing Adenovirus

Name 
Ad-h-GPSN2-shRNA
Cat No 
shADV-210447
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TECR.

shADV-210447
Ad-h-GPSN2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TECR (trans-2,3-enoyl-CoA reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
epididymis secretory sperm binding protein; glycoprotein, synaptic 2; GPSN2; MRT14; SC2; synaptic glycoprotein SC2; TER; Trans-2,3-enoyl-CoA reductase; very-long-chain enoyl-CoA reductase
Description (eCommerce)
TECR is a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA [taken from NCBI Entrez Gene (Gene ID: 9524)].
Description (Vector)
TECR encodes a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA. Alternatively spliced transcript variants have been found for this gene.
Gene ID
9524
Gene Name (eCommerce)
trans-2,3-enoyl-CoA reductase
Gene Name (Vector)
trans-2,3-enoyl-CoA reductase
Gene Symbol
TECR
HGNC ID
HGNC:4551
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
927
Protein Name (eCommerce)
Very-long-chain enoyl-CoA reductase
RefSeq ID
NM_138501
RefSeq Synonyms
NM_138501, NM_001321170, BC013881, BC007801, BC005952, BC002425,
Research Areas
Metabolism/Metabolic Process,Neurobiology
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
TECR is a multi-pass membrane protein that resides in the endoplasmic reticulum, and belongs to the steroid 5-alpha reductase family. The elongation of microsomal long and very long chain fatty acid consists of 4 sequential reactions. This protein catalyzes the final step, reducing trans-2,3-enoyl-CoA to saturated acyl-CoA [taken from NCBI Entrez Gene (Gene ID: 9524)].
UniGene ID
Hs.515642
UniProt ID (eCommerce)
Q9NZ01

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.