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human GP9 shRNA silencing Adenovirus

Name 
Ad-h-GP9-shRNA
Cat No 
shADV-210193
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GP9.

shADV-210193
Ad-h-GP9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GP9 (glycoprotein IX platelet). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD42a; GPIX
Description (Vector)
GP9 encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Gene ID
2815
Gene Name (Vector)
glycoprotein IX platelet
Gene Symbol
GP9
HGNC ID
HGNC:4444
ORF Size (aa)
534
RefSeq ID
NM_000174
RefSeq Synonyms
NM_000174, BC030229,
Species
human
UniGene ID
Hs.1144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.