human GP6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GP6.
shADV-210191
Ad-h-GP6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GP6 (glycoprotein VI platelet). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDPLT11; GPIV; GPVI
Description (Vector)
GP6 encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
51206
Gene Name (Vector)
glycoprotein VI platelet
Gene Symbol
GP6
HGNC ID
HGNC:14388
ORF Size (aa)
1020
ORF Size (bp)
1020 bp
RefSeq ID
NM_016363
RefSeq Synonyms
NM_016363, NM_001256017, NM_001083899, BC111963, BC104832,
Species
human
UniGene ID
Hs.661752
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.