human GOT2 shRNA silencing Adenovirus

Name 
Ad-h-GOT2-shRNA
Cat No 
shADV-210187
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GOT2.

shADV-210187
Ad-h-GOT2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GOT2 (glutamic-oxaloacetic transaminase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
aspartate aminotransferase 2; aspartate aminotransferase, mitochondrial; aspartate transaminase 2; FABP-1; FABPpm; fatty acid-binding protein; glutamate oxaloacetate transaminase 2; glutamic-oxaloacetic transaminase 2, mitochondrial; KAT4; KATIV; KYAT4; kynurenine aminotransferase 4; kynurenine aminotransferase IV; kynurenine--oxoglutarate transaminase 4; kynurenine--oxoglutarate transaminase IV; mAspAT; mitAAT; plasma membrane-associated fatty acid-binding protein; transaminase A
Description (eCommerce)
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology [taken from NCBI Entrez Gene (Gene ID: 2806)].
Description (Vector)
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
Gene ID
2806
Gene Name (eCommerce)
glutamic-oxaloacetic transaminase 2
Gene Name (Vector)
glutamic-oxaloacetic transaminase 2
Gene Symbol
GOT2
HGNC ID
HGNC:4433
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1293
ORF Size (bp)
1293 bp
Protein Name (eCommerce)
Aspartate aminotransferase, mitochondrial
RefSeq ID
NM_002080
RefSeq Synonyms
NM_002080, NM_001286220, BC000525,
Research Areas
Metabolism/Metabolic Process,Mitochondrion
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology [taken from NCBI Entrez Gene (Gene ID: 2806)].
UniGene ID
Hs.599470
UniProt ID (eCommerce)
P00505

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.