human GLRB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GLRB.
shADV-209994
Ad-h-GLRB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GLRB (glycine receptor beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HKPX2
Description (Vector)
GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.
Gene ID
2743
Gene Name (Vector)
glycine receptor beta
Gene Symbol
GLRB
HGNC ID
HGNC:4329
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_000824
RefSeq Synonyms
NM_001166061, NM_001166060, NM_000824, BC032635,
Species
human
UniGene ID
Hs.32973
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.