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human GFRA2 shRNA silencing Adenovirus

Name 
Ad-h-GFRA2-shRNA
Cat No 
shADV-209833
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GFRA2.

shADV-209833
Ad-h-GFRA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GFRA2 (GDNF family receptor alpha 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
87
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GDNFRB; NRTNR-ALPHA; NTNRA; RETL2; TRNR2
Description (Vector)
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
2675
Gene Name (Vector)
GDNF family receptor alpha 2
Gene Symbol
GFRA2
HGNC ID
HGNC:4244
ORF Size (aa)
1395
ORF Size (bp)
1395 bp
RefSeq ID
NM_001495
RefSeq Synonyms
NM_001495, NM_001165039, NM_001165038, BC041688,
Species
human
UniGene ID
Hs.441202

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.