human GAR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GAR1.
shADV-209644
Ad-h-GAR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GAR1 (GAR1 ribonucleoprotein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NOLA1
Description (Vector)
GAR1 is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.
Gene ID
54433
Gene Name (Vector)
GAR1 ribonucleoprotein
Gene Symbol
GAR1
HGNC ID
HGNC:14264
ORF Size (aa)
654
ORF Size (bp)
654 bp
RefSeq ID
NM_018983
RefSeq Synonyms
NM_032993, NM_018983, BC003413,
Species
human
UniGene ID
Hs.69851
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.