human GAD2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GAD2.
shADV-209539
Ad-h-GAD2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GAD2 (glutamate decarboxylase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GAD65
Description (Vector)
GAD2 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. GAD2 may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Gene ID
2572
Gene Name (Vector)
glutamate decarboxylase 2
Gene Symbol
GAD2
HGNC ID
HGNC:4093
ORF Size (aa)
1758
ORF Size (bp)
1758 bp
RefSeq ID
NM_000818
RefSeq Synonyms
NM_001134366, NM_000818, BC126329, BC126327,
Species
human
UniGene ID
Hs.231829
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.