human GABRB3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human GABRB3.
shADV-209520
Ad-h-GABRB3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ECA5; EIEE43
Description (Vector)
GABRB3 encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene ID
2562
Gene Name (Vector)
gamma-aminobutyric acid type A receptor beta3 subunit
Gene Symbol
GABRB3
HGNC ID
HGNC:4083
ORF Size (aa)
1422
ORF Size (bp)
1422 bp
RefSeq ID
NM_000814
RefSeq Synonyms
NM_021912, NM_001278631, NM_001191321, NM_001191320, NM_000814, BC010641,
Species
human
UniGene ID
Hs.657298
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.